math.ST

Estimating the Expected Value of Sample Information across Different Sample Sizes using Moment Matching and Non-Linear Regression

Background: The Expected Value of Sample Information (EVSI) determines the economic value of any future study with a specific design aimed at reducing uncertainty in a health economic model. This has potential as a tool for trial design; the cost and …

Efficient Monte Carlo Estimation of the Expected Value of Sample Information using Moment Matching

The Expected Value of Sample Information (EVSI) is used to calculate the economic value of a new research strategy. While this value would be important to both researchers and funders, there are very few practical applications of the EVSI. In the …